Reduces calorie intake by inhibiting appetite and increasing satiety, elevates metabolism and increases calorie intake.
Take 1 -2capsule daily in an exceedingly fast.
Indicated for weight loss and maintenance of lost weight.
Sibutramine belongs to a gaggle of medicines called anti-obesity medicines that may facilitate your slim down and maintain it.
It works by increasing the activity of two chemicals within the brain, called norepinephrine and serotonin thus promoting a sense of getting eaten enough (satiety) and reducing food intake, ends up in gradual weight loss.
Sibutramine is employed as a component of a comprehensive weight management program to treat:
– Patients with obesity-related diet and a body mass index (BMI *) of 30 kg / m² or more;
– Overweight-related patients and other obesity / overweight related risk factors like diabetes or abnormal levels of fat within the blood.
Sibutramine could be a central acting stimulant and is well absorbed by the alimentary canal (77%), undergoes a substantial metabolism that reduces its bioavailability.
Pharmacological aspects of sibutramine
Sibutramine could be a neurotransmitter reuptake inhibitor that helps increase satiety by inhibiting serotonin reabsorption by 73%), norepinephrine (by 54%) and dopamine (by 16%). Sibutramine was approved by the US Food and Drug Administration (FDA) as a weight-loss drug for obesity treatment in November 1997.
CONTRAINDICATIONS:
Sibutramine is contraindicated in cases of:
Psychiatric conditions like bulimia nervosa, anorexia, severe depression, or pre-existing mania.
Hypersensitivity to the drug
Patients under 18 years old.
Concomitant treatment with antidepressants or other centrally active medicines.
Hypertension not sufficiently controlled.
Pulmonary hypertension.
Cardiac lesions, coronary disease, congestive heart disease, severe arrhythmia, and former infarction.
Infarction or transient ischemic attack.
Hyperthyroidism.
Closed angle glaucoma.
Problems of apoplectic attack.
Enlargement of the prostate with retentiveness.
Pheochromocytoma.
Pregnant women.
POSSIBLE SIDE EFFECTS
SIBUTRAMINE can cause side effects, although no person gets them. Most effects can occur during the primary 2 weeks of treatment and settle down pronounced over time.
The most common side effects are dryness and different taste within the mouth.
HOW TO TAKE SIBUTRAMINE
1 Capsule of 20mg of Sibutramine, every morning at the identical time in fasting, with water.
Do not take over 40mg (2 capsules) per day.
* The BMI is calculated by dividing the burden in kilograms by the square of its height in meters (kg / m2). People are obese once they have a Body Mass Index (BMI) of 30 kg / m² or more. an individual is overweight once they have a BMI between 25 and 30 kg / m².
Results:
With Sibutramine 20mg you’ll lose up to 12kg in one month, reckoning on the body
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